Antibacterial Activity Of Bungur Bark Extract (Lagerstroemia speciosa (L.) Pers) Againts Staphylococcus aureus ATCC 29213 By Diffusion And Dillution Methods.
Keywords:
Antibacterial, S. aureus ATCC 29213, Lagerstroemia bark.Abstract
Staphylococcus aureus is one of the multidrug resistance pathogenic bacteria which is emphasized by supervision world health organization because it has characteristics that easily avoid the target of antibiotic activity and resistant to various antibiotics. It narrows the choice of treatment. Bungur bark is a plants that has potential as an antibacterial, it is necessary to explore its activities as a new alternative medicine. This study aims to determine Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of Bungur bark extract against S. aureus ATCC 29213. This type of research is true experimental with post test only with control goup design with 5 treatment groups namely 25%, 50%, 75%, 100%, ciprofloxacin as a positive control and negative control without treatment using diffusion and dilution methods with determination of MIC and MBC. The results showed that Bungur bark had inhibition zone against S. aureus ATCC 29213 at a concentrations of 25%, 50%, 75% and 100% is 7.23 mm, 11.73 mm, 17.51 mm and 21.09 mm with MIC values at 100% concentration. As for the dilution method, there was no MBC againts S. aureus ATCC 29213. The results showed that MIC of Bungur bark was at a concentration of 100% . As for the MBC test, Bungur bark did not show any killing power against S. aureus ATCC 29213.
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Vensia Magdalena, N., & Kusnadi, J. (2015). Antibakteri Dari Ekstrak Kasar Daun Gambir (Uncaria gambir var Cubadak) Metode Microwave-Assisted Extraction Terhadap Bakteri Patogen Antibacterial from Gambier Leaves Crude Extract (Uncaria gambir var Cubadak) Microwave-Assisted Extraction Method against. Jurnal Pangan Dan Agroindustri, 3(1), 124–135.
Zamilah, M., Ruhimat, U., & Setiawan, D. (2020). Media Alternatif Kacang Tanah Untuk Pertumbuhan Bakteri. Journal of Indonesian Medical Laboratory and Science, 116(1), 32–47.
Arinda, Y., Fitriana, N., Arfiana, V., Fatimah, N., & Shabrina, A. (2019). Aktivitas Anti Bakteri Daun Sirih : Uji Ekstrak KHM ( Kadar Hambat Minimum ) dan KBM ( Kadar Bakterisidal Minimum ). 16(2), 101–108.
Bawondes, J. N., Maarisit, W., Ginting, A., & Kanter, J. (2021). Uji Aktivitas Antibakteri Ekstrak Etanol Buah Awar-Awar Ficus septica Burm . F Terhadap Bakteri Staphylococcus aureus. Jurnal Biofarmasetika Tropis, 4(1), 21–29.
Brigitta, P., Nengah, N., Fatmawati, D., Nyoman, N., Budayanti, S., Mikrobiologi, D., Kedokteran, F., & Udayana, U. (2021). Uji Aktivitas Ekstrak Etanol Daun Sambiloto (Andrographis paniculata Nees) Sebagai Anti Bakteri Streptococcus pyogenes ATCC 19615 1. 10(3), 94–98.
Chaudhry, B., Alekseyev, K., Didenko, L., & Ryklin, G. (2021). Post COVID-19 MSSA pneumonia. https://doi.org/10.1177/2050313X211005996
Erlina, M., Farmasi, F., & Surakarta, U. M. (2021). Uji Aktivitas Antibakteri Ekstrak Umbi Porang (Amorphophallus Muelleri Blume), Suweg (Amorphophallus Paeoniifolius), Iles-Iles (Amorphophallus Oncophyllus) dan Walur (Amorphophallus Campanulatus). 622–631.
Handayani, W., Dwi, A., Octavia, A., & Safitri, E. (2020). Uji In Vitro Interaksi Cefadroxil dengan Pisang dan Susu terhadap Bakteri Staphylococcus aureus dengan Metode Difusi Cakram In Vitro Test of Cefadroxil Interaction with Banana and Milk Against Staphylococcus aureus using Disc Difusion Method. 5(2), 87–91.
J, P. A., & Shah, M. (2020). A Systematic review on Banaba. 7(1), 608–616. www.ijrar.org
Kurniawan, E., Soelistya, D., Jekti, D., & Zulkifli, L. (2019). Jurnal Biologi Tropis Aktivitas Antibakteri Ekstrak Metanol Batang Bidara Laut ( Strychnos ligustrina ) Terhadap Bakteri Patogen. https://doi.org/10.29303/jbt.v19i1.1040
Mahdiyah, D., Farida, H., Riwanto, I., Mustofa, M., Wahjono, H., Laksana, T., & Reki, W. (2020). Saudi Journal of Biological Sciences Screening of Indonesian peat soil bacteria producing antimicrobial compounds. Saudi Journal of Biological Sciences, 27(10), 2604–2611. https://doi.org/10.1016/j.sjbs.2020.05.033
Monaco, M., Araujo, F. P. de, Cruciani, M., Coccia, E. M., & Pantosti, A. (2017). Worldwide Epidemiology and Antibiotic Resistance of Staphylococcus aureus. Springer International Publishing Switzerland, 37(March), 21–56. https://doi.org/10.1007/82
Noval, N., Yuwindry, I., & Syahrina, D. (2019). Phytochemical Screening and Antimicrobial Activity of Bundung Plants Extract by Dilution Method. Jurnal Surya Medika, 5(1), 143–154. https://doi.org/10.33084/jsm.v5i1.954
Nuryah, A., Yuniarti, N., & Puspitasari, I. (2019). Prevalensi dan Evaluasi Kesesuaian Penggunaan Antibiotik pada Pasien dengan Infeksi Methicillin Resistant Staphylococcus Aureus di RSUP Dr. Soeradji Tirtonegoro Klaten. Majalah Farmaseutik, 15(2), 123. https://doi.org/10.22146/farmaseutik.v15i2.47911
Owu, N. M., & Jayanti, M. (2020). Uji Efektivitas Penghambatan Dari Ekstrak Daun Sirih (Piper Betle L.) Terhadap Bakteri Streptococcus mutans. Jurnal Biomedik : Jbm, 12(3), 145–152. https://doi.org/10.35790/jbm.12.3.2020.29185
Pehino, A., & Suoth, E. J. (2021). Antibacterial Activity Test Of Duku Fruit Seeds (Lansium domesticum) Againts Staphylococus aureus And Escherichia coli Bacteries. 10, 6–12.
Putri, D. A., Roebiakto, E., & Dwiyanti, R. D. (2018). Staphylococcus aureus pada keyboard di unit pelayanan penunjang rumah sakit. Jurnal Skala Kesehatan, 9(1). https://doi.org/10.31964/jsk.v9i1.150
Rahmah, S. M., Dharmono, & Putra, A. P. (2021). Kajian etnobotani tumbuhan bungur ( Lagerstroemia Speciosa ) di Kawasan Hutan Bukit Tamiang Kabupaten Tanah Laut sebagai buku ilmiah populer. BIODIK: Jurnal Ilmiah Pendidikan Biologi, 7(1), 1–12.
Rahmitasari, R. D., Suryani, D., & Hanifa, N. I. (2020). Aktivitas Antibakteri Ekstrak Etanolik Daun Juwet ( Syzygium cumini ( L .) Skeels ) terhadap Bakteri Isolat Klinis Salmonella typhi Antibacterial Activity of Ethanolic Extracts of Java Plum ( Syzygium cumini ( L ) Skeels ) Leaves against Clinical Isolate. Jurnal Farmasi Indonesia, 17(01), 138–148. http://jurnalnasional.ump.ac.id/ [Diakses pada 28 April 2021]
Riyanti, S., Syam, A. K. S., & Firmansyah, A. (2020). Senyawa Fenol Dalam Kulit Batang Bungur (Lagerstroemia loudinii Teijsm. & Binn.) Sebagai Sumber Antioksidan. Seminar Nasional Farmasi (SNIFA) 4 UNJANI, June, 133–135. https://www.researchgate.net/publication/342049710
Supriani, & Nurwijayanti. (2021). Uji kandungan fitokimia dan aktivitas antibakteri dari ekstrak etanolik bawang dayak terhadap bakteri staphylococcus aureus dalam media mueller hinton agar. 10(1), 1–6.
Utomo, S. B., Fujiyanti, M., Lestari, W. P., & Mulyani, S. (2018). Antibacterial Activity Test of the C-4 methoxyphenylcalix[4]resorcinarene Compound Modified by Hexadecyltrimethylammonium-Bromide against Staphylococcus aureus and Escherichia coli Bacteria. JKPK (Jurnal Kimia Dan Pendidikan Kimia), 3(3), 201. https://doi.org/10.20961/jkpk.v3i3.22742
Vensia Magdalena, N., & Kusnadi, J. (2015). Antibakteri Dari Ekstrak Kasar Daun Gambir (Uncaria gambir var Cubadak) Metode Microwave-Assisted Extraction Terhadap Bakteri Patogen Antibacterial from Gambier Leaves Crude Extract (Uncaria gambir var Cubadak) Microwave-Assisted Extraction Method against. Jurnal Pangan Dan Agroindustri, 3(1), 124–135.
Zamilah, M., Ruhimat, U., & Setiawan, D. (2020). Media Alternatif Kacang Tanah Untuk Pertumbuhan Bakteri. Journal of Indonesian Medical Laboratory and Science, 116(1), 32–47.
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