THE EFFECT OF DAYAK ONION BOOTER EXTRACT (ELEUTHERINE PALMIFOLIA (L.) MERR ) AS ANTI-BREAST CANCER: LITERATURE REVIEW

Main Article Content

Triska Dayanti
Novalia Widya Ningrum
Desilestia Dwi Salmarini

Abstract

Latar Belakang: Kanker payudara merupakan tumor  yang menyerang jaringan sel-sel payudara  Sekitar 8-9% wanita menderita penyakit kanker payudara kasus kanker payudara terus meningkat lebih dari 250,000 kasus baru, di Eropa 178.000 wanita yang telah di diagnosis kanker payudara, prevalensi kanker payudara di Indonesia 1,4 per 100 penduduk atau 347.000 orang. Kanker payudara di Kalimantan selatan pada tahun 2019 tercatat sebanyak 262 oarng.

Tujuan: Mengetahui Pengaruh Ekstrak Umbi Bawang Dayak (Eleutherine palmifolia (L.) Merr) Sebagai Antikanker Payudara.

Metode: Rancangan penelitian ini adalah  Literatuure Review. Kriteria artikel diambil berdasarkan kata kunci,tahun,judul,abstrak,full paper dan menjawab tujuan penelitian yang bersumber dari Google scholar dan Pudmed. Jumlah artikel yang digunakan dalam penelitian ini sebanyak 10 artikel.

Hasil: Berdasarkan 10 artikel yang telah di telaah menyatakan bahwa bawang dayak (Eleutherine Palmifolia (L.) Merr) mengandung senyawa yang dapat menghambat sel kanker dan sudah dilakukan uji menggunakan sel kanker yang hidup dengan menggunakan metode  MTT assay, namun perlu adanya penelitian lanjutan agar ekstrak bawang dayak dapat dijadikan obat herbal.

Kesimpulan: Bahwa bawang dayak memiiki senyawa yang dapat mengahambat sel kanker payudara hingga dapat memusnahkan sel kanker namun perlu adanya penelitian lanjutan untuk memastikan bawang dayak dapat dikonsumsi secara langsung dalam bentuk obat.

 

Kata Kunci : Antikanker Payudara, Bawang Dayak (Eleutherine palmifolia (L.) Merr, Pengaruh Ekstrak

 

Background: Breast cancer is a tumor that attacks breast tissue. About 8-9% of women suffer from breast cancer. Breast cancer cases continue to increase, more than 250,000 new cases, in Europe 178,000 women have been diagnosed with breast cancer, the prevalence of breast cancer in Indonesia is 1.4 per 100 population or 347,000 people. Breast cancer in South Kalimantan in 2019 was recorded at 262 people.

Objective: Effect of Dayak Onion (Eleutherine palmifolia (L.) Merr) Extract as Anticancer Breast.

Methods: The design of this research is a Literature Review. The criteria for articles are taken based on keywords, year, title, abstract, full paper, and answer research objectives sourced from Google Scholar and PubMed. The number of articles used in this study was 10 articles.

Results: Based on 10 articles that have been reviewed, it states that the Dayak onion (Eleutherine palmifolia (L.) Merr) contains compounds that can inhibit cancer cells and has been tested using live cancer cells using the MTT assay method, but further research is needed so that the extract Dayak onions can be used as herbal medicine.

Conclusion: That Dayak onions have compounds that can inhibit breast cancer cells so that they can destroy cancer cells, but further research is needed to ensure that Dayak onions can be consumed directly in the form of medicine.

 

Keywords: Breast Anticancer, Dayak Onion (Eleutherine palmifolia (L.) Merr, Effect of Extract.


 

Abstract

Breast cancer is a tumor that attacks breast tissue. About 8-9% of women suffer from breast cancer. Breast cancer cases continue to increase, more than 250,000 new cases, in Europe 178,000 women have been diagnosed with breast cancer, the prevalence of breast cancer in Indonesia is 1.4 per 100 population or 347,000 people. Breast cancer in South Kalimantan in 2019 was recorded at 262 people.Effect of Dayak Onion (Eleutherine palmifolia (L.) Merr) Extract as Anticancer Breast. The design of this research is a Literature Review. The criteria for articles are taken based on keywords, year, title, abstract, full paper, and answer research objectives sourced from Google Scholar and PubMed. The number of articles used in this study was 10 articles.

Based on 10 articles that have been reviewed, it states that the Dayak onion (Eleutherine Palmifolia (L.) Merr) contains compounds that can inhibit cancer cells and has been tested using live cancer cells using the MTT assay method, but further research is needed so that the extract Dayak onions can be used as herbal medicine.That Dayak onions have compounds that can inhibit breast cancer cells so that they can destroy cancer cells, but further research is needed to ensure that Dayak onions can be consumed directly in the form of medicine.

Article Details

How to Cite
Dayanti, T., Ningrum, N. W., & Salmarini, D. D. (2022). THE EFFECT OF DAYAK ONION BOOTER EXTRACT (ELEUTHERINE PALMIFOLIA (L.) MERR ) AS ANTI-BREAST CANCER: LITERATURE REVIEW. Proceeding Of Sari Mulia University Midwifery National Seminars, 3(1). https://doi.org/10.33859/psmumns.v3i1.841
Section
Articles

References

American Cancer Society, 2019. Endometrial Cancer: American Cancer Society.https://www.cancer.org/cancer/endometrial-cancer.html. [Accessed April 10, 2021].
Badan POM RI, 2011. Reference for Herbal Preparations Volume 6 Edition 1. Jakarta: BPOM RI
Basic Health Research . 2018. Indonesian Ministry of Health Research and Development Agency 2018. [Internet]AvailableAt:https://www.depkes.go.id/article/view/19020100003/hari-kanker-sedunia-2019.html-Accessed December 2019.[Accessed April 10, 2021].


Candra M. Putri, V., Pharmacy, PS, Pharmacy, F., & Surakarta, UM 2021. Literature review: breast anticancer activity of Dayak onion (Eleutherine bulbosa (Mill.) Urb.). Scientific Publications:UMS digital library. http://eprints.ums.ac.id/89952/2/Naskah%20Publikasi_Meylita%20Candra%20Victora%20Putri_K100170196%20%286%29.pdf.[Accessed 10 April 2021]
Erika Nuur Anisa Putri, Haryono, 2018. Anticancer Activity of Ethanol Extract of Dayak Onion Tubers (Eleutherine Americana Merr) Against T47D Breast Cancer Cells. Scientific Publications: UMS digital library http://repository.urecol.org./index.php/proceeding/article/view/172 [Accessed April 10, 2021].
Imran M., Rauf, A., Abu-Izneid, T., Nadeem, M., Shariati, MA, Khan, IA, Imran, A., Orhan, IE, Rizwan, M., Atif, M., Gondal, TA, & Mubarak, MS 2019. Luteolin, a flavonoid, as an anticancer agent: A review. Biomedicine and Pharmacotherapy, 112https://doi.org/10.1016/j.biopha.2019.108612 [Accessed April 10, 2021]
Ministry of Data and Information Center, 2015;https://pusdatin.kemkes.go.id/download.php?file=download/pusdatin/buletin/buletin-kanker.pdf [Accessed 10 April 2021]
Muti'ah, R., Listiyana, A., Nafisa, BB, & Suryadinata, A. (2020). Study of the Effects of Dayak Onion (Eleutherine palmifolia (L.) Merr) Extract as Anticancer. Journal of Islamic Pharmacy, 5(2).https://doi.org/10.18860/jip.v5i2.9778 [Accessed April 10, 2021]
Mutiah Hadya MC., M'arif Burhan, ZA, Bhagawan, SW., Annisa, R., Indrawijaya, YYE., Huwaida, IS., Ramadhani RDA., Susilowati, R., Taufik, I., 2019. Metabolite Fingerprinting of Eleutheine palmifolia (L.) Merr. By HPTLC-Densitometry and its correlation with anticancer avtivities and in vivo toxicity. Indonesia : Journal of pharmacy [Internet]http://dx.doi.org/10.14499/indonesianjpharm30iss3pp157. [Accessed 10 April 2021]
Mutiah, R., Minggarwati ST, Kristanti AR, Susanti, E. 2019. Combinational effect of Eleutherine 15 palmifolia (L.) merr extract and doxorubicin chemotherapy on HeLa cervical cancer cells. AIP Conference Proceedings. Volumes 10(3)https://doi.org/10.1063/1.5115718. [Accessed April 10, 2021]
Nursalam. 2014. Methodology of Nursing Research Practice Approach Edition 3. Jakarta: salemba medika.
Peter, EE 2012. Critical thinking: Essence for teaching mathematics and mathematics problem solving skills. African Journal of Mathematics and Computer Science Research. 5(3): Pages 39-43. https://doi.org/10.5897/AJMCSR11.161 [Accessed April 10, 2021]
Poerwosusanta Hery, Potential of Dayak Onion (Eleutherine Sp) Extract as Standardized Herbal Medicine (OHT) in Medical Medicine. Scientific Journal of Ibn Sina,3(2),242-251. https://repodosen.ulm.ac.id/handle/123456789/18690. [Accessed April 10, 2021]
Prayitno B., Mukti, BH, & Lagiono. (2018). Optimization of the potential of Dayak onion (Eleutherine sp.) as an alternative medicine. Journal of Biological Education, 4(3), 149–158. https://jurnal.stkipbjm.ac.id/index.php/J PH/article/view/436 [Accessed April 10, 2021]
Putri, ENA (2018). Cytotoxic test of the combination of ethanol extract of Dayak onion bulbs (Eleutherine americana Merr.) and soursop seeds (Annona muricata) with methotrexate against T47D cells. Scientific Publications:UMS digital library.https://core.ac.uk/download/pdf/148619303.pdf. [Accessed April 10, 2021].
Widayanti, R. Rompas, ALA, II2019. Effect of Dayak Onion Extract on Neoplasm Growth in DMBA-induced Sprauge-Dauley Rats Orally. Palangkaraya Medical Journal, Vol VII NO 02.https://ejournal.upr.ac.id/index.php/JK/article/view/584.[Accessed April 10
Yuniarti A., Sundhani, E., & Nurulita, NA (2018). The potentiation effect of Bawang Dayak (Sisyrinchium palmifolium L.) extracts on T47D cell growth inhibition after 5-fluorouracil treatment. Pharmaciana, 8(2), 204.:https://doi.org/10.12928/pharmaciana.v8i2.9480.[Accessed April 10, 2021]

Most read articles by the same author(s)

1 2 > >>