KEPATUHAN MINUM OBAT PADA ANAK DENGAN EPILEPSI: LITERATURE REVIEW

Authors

  • Masliani Masliani Program Studi Sarjana Keperawatan, Fakultas Kesehatan, Universitas Sari Mulia
  • Paul Joae Brett Nito Program Studi Sarjana Keperawatan, Fakultas Kesehatan, Universitas Sari Mulia
  • Nur Lathifah Program Studi Sarjana Keperawatan, Fakultas Kesehatan, Universitas Sari Mulia

Keywords:

Epilepsi pada Anak, Kepatuhan Minum Obat, dan Pasien Epilepsi

Abstract

Latar Belakang: Terapi utama yang diberikan kepada penderita epilepsi adalah OAE (Obat Anti Epilepsi). Terapi tersebut digunakan jangka panjang, yang bertujuan fokus untuk mencegah terjadinya kejang. Lamanya pengobatan yang di jalani oleh pasien epilepsi membuat peluang terjadinya ketidakpatuhan dalam meminum obat semakin besar.

Tujuan: Penelitian ini bertujuan menganalisis kepatuhan minum obat pada pasien dengan epilepsi.

Metode: Penelitian ini menggunakan Literature review, dalam pencarian literatur bersumber dari Google scholar, Pubmed, menggunakan kata kunci yang sesuai dengan tema.

Hasil: Kepatuhan minum obat pada pasien dengan epilepsi, dipengaruhi oleh beberapa faktor yaitu faktor inklusi meliputi usia, jenis kejang, jenis obat dan jumlah  obat yang diberikan. Faktor eksklusi meliputi  keluaraga, keluarga yang lebih kecil, status pernikahan orang tua yang stabil, dan status sosial ekonomi keluarga yang lebih tinggi berhubungan dengan kepatuhan pengobatan yang lebih baik. ketidakpatuhan dapat terjadi pada pasien dengan durasi pengobatan yang lama dan kompleksitas obat.

Simpulan: Jangka waktu pengobatan yang baik dan efisien akan  membuat kepatuhan minum obat yang baik. Oleh karena itu diharapkan dukungan keluarga untuk patuh minum obat sehingga menurunkan frekuensi kejang berulang.

 

Background: The main therapy given to people with epilepsy is OAE (Anti Epileptic Medicine). This therapy is used long-term, which aims to focus on preventing seizures. The length of treatment taken by epilepsy patients makes the chances of non-adherence in taking medication even greater.

Aims: This study aims to analyze medication adherence in patients with epilepsy.

Methods: This study uses a literature review, in search of literature sourced from Google scholar, Pubmed, using keywords that match the theme.

Results: Adherence to taking medication in patients with epilepsy is influenced by several factors, namely inclusion factors including age, type of seizure, type of drug and the amount of medication given. Exclusion factors included family, smaller family, stable marital status of parents, and higher family socioeconomic status associated with better medication adherence. non-adherence can occur in patients with long treatment duration and drug complexity.

Conclusions: A good and efficient treatment period will make good medication adherence. Therefore, it is hoped that the support of the family to comply with the medication will reduce the frequency of recurrent seizures.

References

Angelina Hendesa, R.M. Suryadi Tjekyan, Pariyana. 2018. Hubungan Pengetahuan, Sikap, Dan Dukungan Keluarga Dengan Kepatuhan Berobat Pada Pasien Tuberkulosisparu Di Rs Paru Kota Palembang Tahun 2017. Majalah Kedokteran Sriwijaya. 50(4):1-10. Tersedia pada: file:///C:/Users/Ms301215/AppData/Local/Temp/8565-20083-1-PB-1.pdf

Bano, Safia and Numanb, Ahsan. 2016. Factors influencing antiepileptic drug non-compliance in epileptic patients of Pakistan. Pakistan Journal of Neurological Sciences (PJNS). 11(1):5.tersedia pada: http://ecommons.aku.edu/pjns/vol11/iss1/5

Chunsong Yang, Zilong Hao, Dan Yu, Qunfen Xu, Lingli Zhang. 2018. The prevalence rates of medication adherence and factors influencingadherence to antiepileptic drugs in children with epilepsy: A systematicreview and meta analysis. Journal Epilepsy Research. 142(3): 88-99. Tersedia pada:file:///C:/Users/Ms301215/Documents/02%20DOC%20SKRIPSI%20TERBARU/jurnals%20review/Pubmed/The%20prevalence%20rates%20of%20medication%20adherence.

Chunsong Yang, Dan Yu, Jiayuan Li, Lingli Zhang. 2020. Survey Prevalence of medication adherence and factors influencing adherence toantiepileptic drugs in children with epilepsy from western China. Epilepsy & Behavior.104:1-6. file:///C:/Users/Ms301215/Documents/02%20DOC%20SKRIPSI%20TERBARU/jurnals%20review/Pubmed/Prevalence%20of%20medication%20adherence%20and%20factors%20influencing.pdf


Flora Laville PharmD, Marc Montana PharmD, PhD, Nicolas Roux MD, Pascal Rathelot PharmD, PhD, Roch Giorgi MD, PhD. 2017. Factors limiting adherence to antiepileptic treatment: A French online patient survey. Journal Of Clinical Pharmacy and Therapeutics. Original Article. 43(1):73-79. Tersedia pada: file:///C:/Users/Ms301215/Documents/02%20DOC%20SKRIPSI%20TERBARU/jurnals%20review/Pubmed/epd-308353-33692-antiepileptic_drug_adherence_and_persistence_in_children_with_epilepsy_attending_a_large_tertiary_care_children_s_hospital-a.pdf

Fredrick Ibinda, Peter Odermatt,Symon M. Kariuki, Angelina Kakooza-Mwesige, Ryan G. Wagner,Seth Owusu-Agyei, Honorati Masanja, Anthony K.Ngugi, Caroline K. Mbuba, Victor C. K. Doku, Brian G. Neville, Josemir W.Sander, Charles R. J. C. Newton, and on behalf of the SEEDS writing group. 2017. Magnitude and factors associated with nonadherence toantiepileptic drug treatment in Africa: A cross-sectionalmultisite study. Journal Of The International League Against Epilepsy. 2(2):226–235. Tersedia pada: file:///C:/Users/Ms301215/Documents/02%20DOC%20SKRIPSI%20TERBARU/jurnals%20review/Pubmed/Magnitude%20and%20factors%20associated%20with%20nonadherence.pdf

Ernawati, Iin, and Wardah Rahmatul Islamiyah. 2019. Hubungan Kepatuhan Penggunaan Obat Anti Epilepsi terhadap Kejadian Kejang Pasien Epilepsi menggunakan kuesioner ARMS (Adherence Refill Medication Scale). Journal of Pharmacy and Science. 4 (1):29-34. Tersedia pada: file:///C:/Users/Ms301215/Documents/02%20DOC%20SKRIPSI%20TERBARU/jurnals%20review/Scholar/Hubungan%20Kepatuhan%20Penggunaan%20Obat%20Anti%20Epilepsi%20terhadapKejadian%20Kejang%20Pasien%20Epilepsi.pdf

Horne, R., Weinman, J., Barber, N., Elliot, R., Morgan, M., Cribb, A.& Kellar, I. 2005. Concordance, Adherence & Compliance in Medicine Taking. Centre for Health Care Research. University of Brighton, Falmer, Brighton. Terserah pada:
https://fpsi.mercubuanayogya.ac.id/wpcontent/uploads/2012/06/Noor-Kepatuhan...pdf


Jayakara Shetty,Stephen A Greene,Oscar Mesalles-Naranjo,Martin Kirkpatrick. 2015.Adherence to antiepileptic drugs in children with epilepsy in aScottish population cohort. Developmental Medicine & Child Neurology. Original Article. 58 (11) ; 469–474. Tersedia pada:
file:///C:/Users/Ms301215/Documents/02%20DOC%20SKRIPSI%20TERBARU/jurnals%20review/Pubmed/Adherence%20to%20antiepileptic%20drugs\

Mawuntu, Arthur HP, Corry N. Mahama, Sekplin AS Sekeon, Karema Winifred, and Herlyani Khosama. 2019. Kepatuhan Minum Obat Antiepilepsi Pada Pasien Epilepsi Di Manado.Indonesia. Jurnal Sinaps, 2 (3):19-18. Tersedia pada : file:///C:/Users/Ms301215/Documents/02%20DOC%20SKRIPSI%20TERBARU/jurnals%20review/Scholar/KEPATUHAN%20MINUM%20OBAT%20ANTIEPILEPSI%20PADA%20PASIEN%20EPILEPSI%20DI%20MANADO.pdf

Mervat Alsous, Imad Hamdan, Mohammad Saleh, James McElnay, Robert Horne, Amira Masri. 2018. Predictors of nonadherence in children and adolescents with epilepsy: A multimethod assessment approach. Jurnal of epilepsy behavior. 85(8):205-211. Tersedia pada : https://www.epilepsybehavior.com/article/S1525-5050(18)30194-X/fulltext

Sanjeev V Thomas, Aparna Nair. 2011. Confronting the stigma of epilepsy. Confronting the stigma of epilepsy. Journal Of Indian Academy of Neurology.14(3): 158-163. Tersedia pada: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=3;spage=158;epage=163;aulast=Thomas

Wiworo Haryani, Dwi Eni Purwati, S. Satrianingsih. Hubungan antara tingkat pendidikan dan status ekonomi dengan kepatuhan perawatan gigi tiruan lepasan. Majalah Kedokteran Gigi Indonesia. 3 (3):888. Tersedia pada: https://jurnal.ugm.ac.id/mkgi/article/view/26806/20660

Yon-Kyong Lee, Young-Mi Ah, Yun Jung Choi,Yoon Sook Cho, Ki Joong Kim, Ju-Yeun Lee. 2016. Antiepileptic drug adherenceand persistence in childrenwith epilepsy attending a largetertiary care children’s hospital. Original article.18 (4): 408-17. Tersedia pada : file:///C:/Users/Ms301215/Documents/02%20DOC%20SKRIPSI%20TERBARU/jurnals%20review/Pubmed/epd-30835333692.antiepileptic_drug_adherence_and_persistence_in_children_with_epilepsy_attending_a_large_tertiary_care_children_s_hospital-a.pdf

World Health Organisation. 2016. Epilepsy. Tersedia pada: http://www.who.int/mediacentre/factsheets/fs999/en/

WHO, 2019. Epilepsy. Avaible diakses tanggal 15 septemper 2016: Tersedia pada: http://www.who.int/mediacenter/factsheets/fs999/

Downloads

Published

2021-06-11

How to Cite

Masliani, M., Nito, P. J. B., & Lathifah, N. (2021). KEPATUHAN MINUM OBAT PADA ANAK DENGAN EPILEPSI: LITERATURE REVIEW. Proceeding of Sari Mulia University Nursing National Seminars, 2(1), 157–166. Retrieved from https://ocs.unism.ac.id/index.php/PROKEP/article/view/185